Multi-analytical identification of the synthetic opioids cychlorphine and methiodone (IC-26) in drug seizures: first detection in Europe

These results highlight the limitations of library-based screening and the value of multi-platform strategies integrating LC-HRMS, LC-MS/MS, and NMR for the early detection of emerging drugs.

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Publication Details

Journal
Clinical Chemistry and Laboratory Medicine (CCLM)
Published
2026-01-09
DOI
https://doi.org/10.1515/cclm-2025-1428
Primary Topic
Forensic Toxicology and Drug Analysis
Type
article
Field-Weighted Citation Impact
0.00
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article

Multi-analytical identification of the synthetic opioids cychlorphine and methiodone (IC-26) in drug seizures: first detection in Europe

Marie Bellouard, Tiphaine Robin, Grégory Pfau, Cindy Feng et al.
Clinical Chemistry and Laboratory Medicine (CCLM)
Forensic Toxicology and Drug Analysis
article

Multi-analytical identification of the synthetic opioids cychlorphine and methiodone (IC-26) in drug seizures: first detection in Europe

Marie Bellouard, Tiphaine Robin, Grégory Pfau, Cindy Feng, J.C. Alvarez, Paméla Duguès, Sevag Chenorhokian, Sabrina Cherki, Maxime Triguel, Gaëtan Herbette, Islam Amine Larabi
article en

Abstract

These results highlight the limitations of library-based screening and the value of multi-platform strategies integrating LC-HRMS, LC-MS/MS, and NMR for the early detection of emerging drugs.

Clinical Chemistry and Laboratory Medicine (CCLM)
Total (France) (FR), Centre National de la Recherche Scientifique (FR), Institut de Chimie des Substances Naturelles (FR), Inserm (FR), Université de Versailles Saint-Quentin-en-Yvelines (FR), Université Paris-Saclay (FR), Assistance Publique – Hôpitaux de Paris (FR), Centre de recherche en Epidémiologie et Santé des Populations (FR), National Observatory (BR)
Openalex Percentile: Top 93%
Forensic Toxicology and Drug Analysis
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Multi-analytical identification of the synthetic opioids cychlorphine and methiodone (IC-26) in drug seizures: first detection in Europe — Marie Bellouard, Tiphaine Robin, et al. · Clinical Chemistry and Laboratory Medicine (CCLM) (2026) | TGRS Research Map | TGRS