X-ray contrast-adjustable 3D printing for multimodal fusion of microCT and histology
The novel methodology of using contrast agents and resin in 3D printing enables the generation of customizable, contrast-specific phantoms and reference structures. These can be straightforwardly segmented from the embedding material, significantly simplifying and enhancing the workflow of multimodal imaging processes. In this study, 3D printed conic reference structures were effectively used to automate and streamline the precise multimodal fusion of microCT and histological imaging.
Authors
- Marieke A. Stammes (ORCID: https://orcid.org/0000-0003-4261-6535)
- Philipp Nolte
- Christian Dullin (ORCID: https://orcid.org/0000-0003-4297-8077)
- Marius Reichardt
- Marcel Brettmacher
- Chris Johann Ackurat
- Christoph Rußmann
Institutions
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Biomedical Primate Research Centre (NL)
- Elettra-Sincrotrone Trieste S.C.p.A. (IT)
- Institute for Transfusion Medicine (US)
- Max Planck Institute of Experimental Medicine (DE)
- University of Göttingen (DE)
Publication Details
- Journal
- Frontiers in Medical Technology
- Published
- 2026-01-09
- DOI
- https://doi.org/10.3389/fmedt.2025.1702201
- Primary Topic
- Advanced X-ray and CT Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.00