Efficacy of fibrin sealant for bedside pleurodesis in patients with prolonged air leak after lung cancer surgery: a comparative study

For patients with PAL after NSCLC resection, bedside pleurodesis using fibrin sealant appears more effective than 50% glucose solution. It offers better initial success rates, significantly reduces air leak duration, and demonstrates a comparable safety profile. These findings support considering fibrin sealant as a primary non-surgical treatment option for this challenging complication.

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Publication Details

Journal
Frontiers in Surgery
Published
2026-01-09
DOI
https://doi.org/10.3389/fsurg.2025.1722846
Primary Topic
Pleural and Pulmonary Diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Efficacy of fibrin sealant for bedside pleurodesis in patients with prolonged air leak after lung cancer surgery: a comparative study

Jiangjiang Liu, Kai Xie, J. Yu, Haifeng Xia et al.
Frontiers in Surgery
Pleural and Pulmonary Diseases
article

Efficacy of fibrin sealant for bedside pleurodesis in patients with prolonged air leak after lung cancer surgery: a comparative study

Jiangjiang Liu, Kai Xie, J. Yu, Haifeng Xia, Zhe Chen, Xin Gu, Jingkang Qi, Bin Wang, Kaifang Pan
article en

Abstract

For patients with PAL after NSCLC resection, bedside pleurodesis using fibrin sealant appears more effective than 50% glucose solution. It offers better initial success rates, significantly reduces air leak duration, and demonstrates a comparable safety profile. These findings support considering fibrin sealant as a primary non-surgical treatment option for this challenging complication.

Frontiers in SurgeryVol. 12
Soochow University (CN), Second Affiliated Hospital of Soochow University (CN), First Affiliated Hospital of Soochow University (CN)
Science and Technology Program of Suzhou
Good health and well-being
Openalex Percentile: Top 94%
Pleural and Pulmonary Diseases
DOIOpen Access PDFOpenAlex
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Efficacy of fibrin sealant for bedside pleurodesis in patients with prolonged air leak after lung cancer surgery: a comparative study — Jiangjiang Liu, Kai Xie, et al. · Frontiers in Surgery (2026) | TGRS Research Map | TGRS