Urinary proteomic profiling reveals diagnostic biomarkers and regulatory networks in myasthenia gravis

This pilot urinary proteomic study provides preliminary evidence for urinary TPD52 as a potential noninvasive biomarker for MG and suggests its possible involvement in MG pathogenesis. These findings offer new insights into the molecular mechanisms of MG and lay a foundation for applying urinary proteomics in neuroimmune disorders.

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Publication Details

Journal
BMC Neurology
Published
2026-01-09
DOI
https://doi.org/10.1186/s12883-025-04623-5
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
Field-Weighted Citation Impact
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article

Urinary proteomic profiling reveals diagnostic biomarkers and regulatory networks in myasthenia gravis

Shi-ge San, Xi Yang, Jing Yang, Kun Meng et al.
BMC Neurology
Myasthenia Gravis and Thymoma
article

Urinary proteomic profiling reveals diagnostic biomarkers and regulatory networks in myasthenia gravis

Shi-ge San, Xi Yang, Jing Yang, Kun Meng, Fan Ye, Chun-hua Wang, Liang Shen, Lianchen Xiao, Zhen-kun Zhu
article en

Abstract

This pilot urinary proteomic study provides preliminary evidence for urinary TPD52 as a potential noninvasive biomarker for MG and suggests its possible involvement in MG pathogenesis. These findings offer new insights into the molecular mechanisms of MG and lay a foundation for applying urinary proteomics in neuroimmune disorders.

BMC NeurologyVol. 26(1)
Hubei University of Arts and Science (CN), Xiangyang Central Hospital (CN), The Fourth People's Hospital of Ningxia Hui Autonomous Region (CN)
Good health and well-being
Openalex Percentile: Top 92%
Myasthenia Gravis and Thymoma
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