Association between thyroid dysfunction and prognosis in patients with liver failure: a systematic review and meta-analysis

Thyroid dysfunction, particularly low FT3 levels, is associated with higher mortality rates in patients with liver failure. These findings suggest that routine thyroid function assessment may help identify high-risk patients. Further well-designed prospective studies are needed to clarify the underlying mechanisms and evaluate the potential therapeutic implications.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-01-09
DOI
https://doi.org/10.3389/fendo.2025.1748907
Primary Topic
Thyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Association between thyroid dysfunction and prognosis in patients with liver failure: a systematic review and meta-analysis

Hongsheng Lu, Shaoyin Bao, Yin Pan, Hozeifa Mohamed Hassan et al.
Frontiers in Endocrinology
Thyroid Disorders and Treatments
article

Association between thyroid dysfunction and prognosis in patients with liver failure: a systematic review and meta-analysis

Hongsheng Lu, Shaoyin Bao, Yin Pan, Hozeifa Mohamed Hassan, Qi Chen, Yanyun Ruan
article en

Abstract

Thyroid dysfunction, particularly low FT3 levels, is associated with higher mortality rates in patients with liver failure. These findings suggest that routine thyroid function assessment may help identify high-risk patients. Further well-designed prospective studies are needed to clarify the underlying mechanisms and evaluate the potential therapeutic implications.

Frontiers in EndocrinologyVol. 16
Taizhou Central Hospital (CN)
Taizhou University
Openalex Percentile: Top 93%
Thyroid Disorders and Treatments
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