Association between Antihistamine Use and Clinical Outcomes in Patients on Maintenance Hemodialysis

H1 antihistamine use, particularly long-term use and first-generation agents, was associated with increased risks of adverse outcomes in patients undergoing HD. These findings suggest that antihistamine use may represent a potential risk marker in this population; however, the observed associations may reflect the presence or severity of pruritus rather than that of a direct causal effect.

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Publication Details

Journal
Kidney Diseases
Published
2026-01-08
DOI
https://doi.org/10.1159/000550392
Primary Topic
Dermatology and Skin Diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Association between Antihistamine Use and Clinical Outcomes in Patients on Maintenance Hemodialysis

Jung Eun Lee, Junseok Jeon, Ji Young Choi, Yu Jeong Lim et al.
Kidney Diseases
Dermatology and Skin Diseases
article

Association between Antihistamine Use and Clinical Outcomes in Patients on Maintenance Hemodialysis

Jung Eun Lee, Junseok Jeon, Ji Young Choi, Yu Jeong Lim, Seok Hui Kang, Bo Yeon Kim, Jun Young Do
article en

Abstract

H1 antihistamine use, particularly long-term use and first-generation agents, was associated with increased risks of adverse outcomes in patients undergoing HD. These findings suggest that antihistamine use may represent a potential risk marker in this population; however, the observed associations may reflect the presence or severity of pruritus rather than that of a direct causal effect.

Kidney DiseasesVol. 12(1)
Samsung Medical Center (KR), Health Insurance Review and Assessment Service (KR), Yeungnam University (KR), Sungkyunkwan University (KR)
National Research Foundation, Health Insurance Review and Assessment Service
Good health and well-being
Openalex Percentile: Top 93%
Dermatology and Skin Diseases
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