Implicit social animations lead to distinct changes of dopaminergic, corticostriatal and thalamocortical functional connectivity in schizophrenia and bipolar disorder

The unique patterns of altered connectivity in SCZ (imbalance between striatothalamic and thalamocortical connectivity), and BPD, while sharing a common pattern of increase between VTA and dorsal striatum, may represent candidate biomarkers of pathophysiological significance, or as biological targets for validating differential therapeutic neuromodulation.

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Publication Details

Journal
Journal of Psychiatric Research
Published
2026-01-09
DOI
https://doi.org/10.1016/j.jpsychires.2026.01.016
Primary Topic
Transcranial Magnetic Stimulation Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Implicit social animations lead to distinct changes of dopaminergic, corticostriatal and thalamocortical functional connectivity in schizophrenia and bipolar disorder

A. Macedo, Ricardo Martins, M. Castelo-Branco, Nuno Gonçalo Gomes Fernandes Madeira et al.
Journal of Psychiatric Research
Transcranial Magnetic Stimulation Studies
article

Implicit social animations lead to distinct changes of dopaminergic, corticostriatal and thalamocortical functional connectivity in schizophrenia and bipolar disorder

A. Macedo, Ricardo Martins, M. Castelo-Branco, Nuno Gonçalo Gomes Fernandes Madeira, João Valente Duarte
article en

Abstract

The unique patterns of altered connectivity in SCZ (imbalance between striatothalamic and thalamocortical connectivity), and BPD, while sharing a common pattern of increase between VTA and dorsal striatum, may represent candidate biomarkers of pathophysiological significance, or as biological targets for validating differential therapeutic neuromodulation.

Journal of Psychiatric ResearchVol. 194
Champalimaud Foundation (PT), Hospitais da Universidade de Coimbra (PT), University of Coimbra (PT)
Fundação para a Ciência e a Tecnologia
Openalex Percentile: Top 94%
Transcranial Magnetic Stimulation Studies
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