Sex differences in trial representation and the cardiovascular effectiveness of newer glucose‐lowering agents in patients with and without type 2 diabetes: A systematic review and meta‐analysis of cardiovascular outcome trials

SGLT-2is and GLP-1RAs provide broadly comparable cardio-kidney benefits across sexes in patients with and without T2D. The lower representation of women in CVOTs warrants attention.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2026-01-08
DOI
https://doi.org/10.1111/dom.70411
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Sex differences in trial representation and the cardiovascular effectiveness of newer glucose‐lowering agents in patients with and without type 2 diabetes: A systematic review and meta‐analysis of cardiovascular outcome trials

Rohan Sanjanwala, Ashish H. Shah, Shuangbo Liu, Erwin Taguiam et al.
Diabetes Obesity and Metabolism
Diabetes Treatment and Management
article

Sex differences in trial representation and the cardiovascular effectiveness of newer glucose‐lowering agents in patients with and without type 2 diabetes: A systematic review and meta‐analysis of cardiovascular outcome trials

Rohan Sanjanwala, Ashish H. Shah, Shuangbo Liu, Erwin Taguiam, Magdaline Zawadka, Setor K. Kunutsor, Mê‐Linh Lê
article en

Abstract

SGLT-2is and GLP-1RAs provide broadly comparable cardio-kidney benefits across sexes in patients with and without T2D. The lower representation of women in CVOTs warrants attention.

Diabetes Obesity and MetabolismVol. 28(3)
St. Boniface Hospital (CA), University of Manitoba (CA)
University of Manitoba, Max Rady College of Medicine, University of Manitoba
Openalex Percentile: Top 93%
Diabetes Treatment and Management
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Sex differences in trial representation and the cardiovascular effectiveness of newer glucose‐lowering agents in patients with and without type 2 diabetes: A systematic review and meta‐analysis of cardiovascular outcome trials — Rohan Sanjanwala, Ashish H. Shah, et al. · Diabetes Obesity and Metabolism (2026) | TGRS Research Map | TGRS