Current state of mammography-based artificial intelligence for future breast cancer risk prediction: a systematic review

Future studies should evaluate models using digital breast tomosynthesis, examine performance for aggressive or advanced breast cancer, include diverse populations, and evaluate both discrimination and model calibration. Prospective evaluations are needed to determine the clinical utility of mammography-based AI models for personalized risk-based breast cancer screening before implementation.

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Publication Details

Journal
JNCI Journal of the National Cancer Institute
Published
2026-01-06
DOI
https://doi.org/10.1093/jnci/djag002
Citations
2
Primary Topic
AI in cancer detection
Type
article
Field-Weighted Citation Impact
104.19
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article

Current state of mammography-based artificial intelligence for future breast cancer risk prediction: a systematic review

Kevin S. Hughes, CM Vachon, Ki Hwan Kim, Han Eol Jeong et al.
2 citations
JNCI Journal of the National Cancer Institute
AI in cancer detection
104.19
article

Current state of mammography-based artificial intelligence for future breast cancer risk prediction: a systematic review

Kevin S. Hughes, CM Vachon, Ki Hwan Kim, Han Eol Jeong, Adam Yala, Kathryn P. Lowry, Karla Kerlikowske
article en
2 citations

Abstract

Future studies should evaluate models using digital breast tomosynthesis, examine performance for aggressive or advanced breast cancer, include diverse populations, and evaluate both discrimination and model calibration. Prospective evaluations are needed to determine the clinical utility of mammography-based AI models for personalized risk-based breast cancer screening before implementation.

JNCI Journal of the National Cancer InstituteVol. 118(3)
Pacific Northwest Diabetes Research Institute (US), University of Wisconsin–Madison (US), Medical University of South Carolina (US), University of California, San Francisco (US), University of Washington (US), Luther University (KR), University of California System (US), Mayo Clinic in Arizona (US), Mayo Clinic in Florida (US), Wisconsin Division of Public Health (US), University of California, Berkeley (US)
Gender equality, Reduced inequalities
Openalex Percentile: Top 0%
AI in cancer detection
104.19
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Current state of mammography-based artificial intelligence for future breast cancer risk prediction: a systematic review — Kevin S. Hughes, CM Vachon, et al. · JNCI Journal of the National Cancer Institute (2026) | TGRS Research Map | TGRS