Integrated Multiomics Analysis Reveals a Migrasome‐Related Signature for Prognosis and Immunotherapy Response in Lung Adenocarcinoma
This study establishes the first migrasome-based prognostic model for LUAD, demonstrating both independent survival prediction capability and clinical utility for identifying immunotherapy beneficiaries. The MIGsig signature provides novel biological insights into migrasome-mediated tumor-immune interactions and represents a promising tool for precision oncology applications in LUAD management.
Authors
- N. Wang
- Qingqing Feng (ORCID: https://orcid.org/0000-0003-0069-4252)
- Ming Jiang
- Ce Liang
- Jiayu Zhou
- Tianye Song
- Hong Gao
- Xu Zhang
Institutions
- Hebei Medical University (CN)
- Shanxi Medical University (CN)
- Fudan University (CN)
- Sir Run Run Shaw Hospital (CN)
- Second Hospital of Hebei Medical University (CN)
- Shanxi Provincial People’s Hospital (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Human Mutation
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1155/humu/8778797
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00