Exploring the Impact of DNA Methylation on Gene Expression in CRC: A Computational Approach for Identifying Epigenetically Regulated Genes in Multi-Omic Datasets
Our study highlights the potential of computational pipelines to uncover epigenetically regulated genes in colorectal cancer. The identified candidate genes provide a hypothesis-generating foundation for refining molecular stratification and guiding future studies aimed at epigenetic biomarker discovery and therapeutic hypothesis development.
Authors
- Federica De Paoli (ORCID: https://orcid.org/0000-0002-8027-5666)
- Susanna Zucca (ORCID: https://orcid.org/0000-0001-8465-632X)
- Paolo Magni (ORCID: https://orcid.org/0000-0001-5955-6829)
- Rossella Tricarico (ORCID: https://orcid.org/0000-0001-7055-7208)
- Andrei Stefan Blindu
- Federico Manai
Institutions
- University of Pavia (IT)
- Istituti Clinici Scientifici Maugeri (IT)
Publication Details
- Journal
- Cancers
- Published
- 2026-01-09
- DOI
- https://doi.org/10.3390/cancers18020211
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fondazione Umberto Veronesi