Hemispherectomy in infants: an institutional experience with 21 patients

An institutional experience demonstrated that functional hemispherectomy is a safe and well-tolerated procedure in infants and offers excellent seizure control outcomes in hemispheric-onset epilepsies. The surgical technique, a focus on minimizing operative blood loss, and multidisciplinary care of these patients are critical elements in ensuring the safety and success of this procedure. Future studies are needed to better characterize long-term functional and neurodevelopmental outcomes in this age group.

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Publication Details

Journal
Journal of Neurosurgery Pediatrics
Published
2026-01-02
DOI
https://doi.org/10.3171/2025.9.peds25241
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Hemispherectomy in infants: an institutional experience with 21 patients

Dominic Nistal, Jason S. Hauptman, Hannah E. Goldstein, Jeffrey G. Ojemann et al.
Journal of Neurosurgery Pediatrics
Epilepsy research and treatment
article

Hemispherectomy in infants: an institutional experience with 21 patients

Dominic Nistal, Jason S. Hauptman, Hannah E. Goldstein, Jeffrey G. Ojemann, Robert T. Buckley, Scott Boop, Richard G. Ellenbogen
article en

Abstract

An institutional experience demonstrated that functional hemispherectomy is a safe and well-tolerated procedure in infants and offers excellent seizure control outcomes in hemispheric-onset epilepsies. The surgical technique, a focus on minimizing operative blood loss, and multidisciplinary care of these patients are critical elements in ensuring the safety and success of this procedure. Future studies are needed to better characterize long-term functional and neurodevelopmental outcomes in this age group.

Journal of Neurosurgery PediatricsVol. 37(3)
Seattle Children's Hospital (US), Phoenix Children's Hospital (US)
Zero hunger
Openalex Percentile: Top 92%
Epilepsy research and treatment
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