Diagnostic Accuracy of Artificial Intelligence in Detecting Pleural Effusion on Ultrasound Imaging: A Systematic Review and Meta‐Analysis

Artificial intelligence (AI) interpretation of ultrasound (US) images is promising, yet its accuracy in diagnosing pleural effusions remains unclear. We conducted a comprehensive database search which identified 84 studies, of which 6 met eligibility criteria. We included 2951 patients with 58 392 images and 12 069 ultrasound clips. Bivariate analysis revealed a pooled sensitivity of 0.92 (95% CI: 0.85-0.96, p < 0.05) and specificity of 0.96 (95% CI: 0.88-0.99, p < 0.05), with a high AUC of 0.98 under the sROC curve, although included studies had significant heterogeneity, I<sup>2</sup> > 99%. AI demonstrates high diagnostic accuracy in detecting pleural effusion on ultrasound.

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Publication Details

Journal
Journal of Clinical Ultrasound
Published
2026-01-08
DOI
https://doi.org/10.1002/jcu.70168
Primary Topic
Ultrasound in Clinical Applications
Type
article
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article

Diagnostic Accuracy of Artificial Intelligence in Detecting Pleural Effusion on Ultrasound Imaging: A Systematic Review and Meta‐Analysis

Teck Yon Lee, Sophia Wong Ching Hwai
Journal of Clinical Ultrasound
Ultrasound in Clinical Applications
article

Diagnostic Accuracy of Artificial Intelligence in Detecting Pleural Effusion on Ultrasound Imaging: A Systematic Review and Meta‐Analysis

Teck Yon Lee, Sophia Wong Ching Hwai
article en

Abstract

Artificial intelligence (AI) interpretation of ultrasound (US) images is promising, yet its accuracy in diagnosing pleural effusions remains unclear. We conducted a comprehensive database search which identified 84 studies, of which 6 met eligibility criteria. We included 2951 patients with 58 392 images and 12 069 ultrasound clips. Bivariate analysis revealed a pooled sensitivity of 0.92 (95% CI: 0.85-0.96, p < 0.05) and specificity of 0.96 (95% CI: 0.88-0.99, p < 0.05), with a high AUC of 0.98 under the sROC curve, although included studies had significant heterogeneity, I<sup>2</sup> > 99%. AI demonstrates high diagnostic accuracy in detecting pleural effusion on ultrasound.

Journal of Clinical Ultrasound
NHS Fife (GB), Northern Health and Social Care Trust (GB)
Openalex Percentile: Top 94%
Ultrasound in Clinical Applications
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