Radioprotective Effect of ε-Aminocaproic Acid in Acute Total-Body Gamma Irradiation in Rats
ε-Aminocaproic acid exerts a pronounced, timing-dependent radioprotective effect in a rat model of acute total-body γ-irradiation, concurrently reducing the severity of radiation enteritis, hematologic toxicity, and early mortality. These findings support further investigation of EACA as a candidate adjunct in the prevention of acute radiation injury.
Authors
- SHYNAR TANABAYEVA
- Ildar Ravisovich Fakhradiyev (ORCID: https://orcid.org/0000-0003-0528-3874)
- Zhomart Beksultanov (ORCID: https://orcid.org/0000-0002-4778-5023)
- Marat Shoranov (ORCID: https://orcid.org/0009-0009-8373-2496)
- Anel Ibrayeva
- Timur Saliev
- Timur Fazylov
- Igor Danko
Institutions
- Kazakh National Medical University (KZ)
- Korea University (KR)
- National Nuclear Center of the Republic of Kazakhstan (KZ)
Publication Details
- Journal
- Life
- Published
- 2026-01-08
- DOI
- https://doi.org/10.3390/life16010096
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 0.00