Identification of Novel Leads as Antitubercular Agents that Target Mtb-DHFR by using Virtual Screening
On the basis of cell-based and enzymatic results, we concluded that Ansh- 04 is a promising, selective Mtb-DHFR inhibitor with potential as an anti-TB lead candidate.
Authors
- Mohammad Mumtaz Alam (ORCID: https://orcid.org/0000-0001-6420-8757)
- Kalicharan Sharma (ORCID: https://orcid.org/0000-0003-0333-2521)
- Milendra Kumar Turkar (ORCID: https://orcid.org/0009-0007-8890-7676)
- Mymoona Akhter
- Divyanshi Thakur
- Mohammad Shaquiquzzaman
Institutions
- Rajiv Gandhi Technical University (IN)
- Jamia Hamdard (IN)
- Indo Soviet Friendship College of Pharmacy (IN)
Publication Details
- Journal
- Current Medicinal Chemistry
- Published
- 2026-01-06
- DOI
- https://doi.org/10.2174/0109298673384603250812175443
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00