Fatigue Associated with Trastuzumab Deruxtecan in Solid Tumors: A Meta-Analysis and Pharmacovigilance Signal Detection Study

T-DXd is associated with substantially increased fatigue risk and high incidence across solid tumors. Early detection, proactive management, and routine monitoring of patientreported outcomes are recommended to support treatment adherence and quality of life.

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Publication Details

Journal
Current Drug Safety
Published
2026-01-05
DOI
https://doi.org/10.2174/0115748863400146251007114813
Primary Topic
Colorectal Cancer Treatments and Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Fatigue Associated with Trastuzumab Deruxtecan in Solid Tumors: A Meta-Analysis and Pharmacovigilance Signal Detection Study

Yongxin Li, Yuyao Tang, Yinyin Ye, Xinlong Tao et al.
Current Drug Safety
Colorectal Cancer Treatments and Studies
article

Fatigue Associated with Trastuzumab Deruxtecan in Solid Tumors: A Meta-Analysis and Pharmacovigilance Signal Detection Study

Yongxin Li, Yuyao Tang, Yinyin Ye, Xinlong Tao, Cheng-Rong Zhang, Jiuda Zhao, Qianyue Ma
article en

Abstract

T-DXd is associated with substantially increased fatigue risk and high incidence across solid tumors. Early detection, proactive management, and routine monitoring of patientreported outcomes are recommended to support treatment adherence and quality of life.

Current Drug SafetyVol. 21
Qinghai University Affiliated Hospital (CN)
Good health and well-being
Openalex Percentile: Top 94%
Colorectal Cancer Treatments and Studies
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