Postoperative Pyoderma Gangrenosum: Rare Infection Mimic and Diagnostic Challenge – A Case Report

Postoperative PG should be considered in non-resolving postoperative wound complications with negative cultures and antibiotic failure. In this context, prior exposure to PARP inhibitors may be a biologically plausible cofactor through immune modulation; however, a causal link remains unproven. Early dermatology consultation and biopsy are essential to avoid harmful debridement and expedite immunosuppression.

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Publication Details

Journal
Visceral Medicine
Published
2026-01-08
DOI
https://doi.org/10.1159/000550349
Primary Topic
Autoimmune and Inflammatory Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Postoperative Pyoderma Gangrenosum: Rare Infection Mimic and Diagnostic Challenge – A Case Report

Clemens Schafmayer, Sebastian Hinz, Saeed Aldarwish
Visceral Medicine
Autoimmune and Inflammatory Disorders
article

Postoperative Pyoderma Gangrenosum: Rare Infection Mimic and Diagnostic Challenge – A Case Report

Clemens Schafmayer, Sebastian Hinz, Saeed Aldarwish
article en

Abstract

Postoperative PG should be considered in non-resolving postoperative wound complications with negative cultures and antibiotic failure. In this context, prior exposure to PARP inhibitors may be a biologically plausible cofactor through immune modulation; however, a causal link remains unproven. Early dermatology consultation and biopsy are essential to avoid harmful debridement and expedite immunosuppression.

Visceral Medicine
University of Rostock (DE)
Good health and well-being
Openalex Percentile: Top 94%
Autoimmune and Inflammatory Disorders
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