A pH-responsive iron/manganese bimetallic organic framework nanosystem for synergistic therapy of colon cancer
A system loaded with MTO and encapsulated in SA achieved efficient drug delivery and tumor- microenvironment-triggered release. This release of MTO further exerted its chemotherapeutic effects and, in conjunction with ferroptosis, induced immunogenic cell death.
Authors
- Xin Yan (ORCID: https://orcid.org/0000-0002-2329-4422)
- Jia Xue
- Mujie Kan
- Chang Liu
- Shichen Zhang
- Caina Xu
- Siyuan Wang
- Yixin Tang
Institutions
- Jilin University (CN)
- First Hospital of Jilin University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1039/d5cc06597f
- Primary Topic
- Metal-Organic Frameworks: Synthesis and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- People's Government of Jilin Province
- Fundamental Research Funds for the Central Universities