Gender and age variations in neuropsychiatric adverse events of cetirizine and levocetirizine: a disproportionality analysis of ICSRs from FAERS and EudraVigilance data
These findings highlight the distinct neuropsychiatric risk profiles associated with cetirizine and levocetirizine. This underscores the importance of age- and sex-informed drug selection to optimize their safe use.
Authors
- Xueliang Yi (ORCID: https://orcid.org/0009-0007-4151-4891)
- Yang Chen (ORCID: https://orcid.org/0000-0002-3667-4862)
- Chunlin Xiang
- Yanru Wang (ORCID: https://orcid.org/0000-0001-8272-2450)
- Xiaoxia Zheng
- Tingting Yang
- Yinping Yang
- Yuhong Han
- Xiaoxiao Wu
Institutions
- University of Electronic Science and Technology of China (CN)
- Affiliated Hospital of Southwest Medical University (CN)
- Chengdu University (CN)
- Dazhou Central Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-01-09
- DOI
- https://doi.org/10.3389/fphar.2025.1737359
- Primary Topic
- Pharmacovigilance and Adverse Drug Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Major Science and Technology Projects of China