Correlation Between Histopathology and Chemotherapy Response in Epithelial Ovarian Tumors

Histopathological subtype is a major determinant of response to neoadjuvant carboplatin-paclitaxel in epithelial ovarian carcinoma. Integrating RECIST response, CA-125 kinetics, CRS, and residual disease provides a pragmatic, histology-informed framework for treatment planning, particularly in settings where molecular profiling is limited.

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Publication Details

Journal
Cureus
Published
2026-01-08
DOI
https://doi.org/10.7759/cureus.101088
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Correlation Between Histopathology and Chemotherapy Response in Epithelial Ovarian Tumors

T Sravanthi, M Ramya, M Srinivasulu, Surekha Talasila
Cureus
Ovarian cancer diagnosis and treatment
article

Correlation Between Histopathology and Chemotherapy Response in Epithelial Ovarian Tumors

T Sravanthi, M Ramya, M Srinivasulu, Surekha Talasila
article en

Abstract

Histopathological subtype is a major determinant of response to neoadjuvant carboplatin-paclitaxel in epithelial ovarian carcinoma. Integrating RECIST response, CA-125 kinetics, CRS, and residual disease provides a pragmatic, histology-informed framework for treatment planning, particularly in settings where molecular profiling is limited.

CureusVol. 18(1)
Gandhi Medical College & Hospital (IN), MNJ Institute Of Oncology and Regional Cancer Centre (IN), Employees State Insurance Post Graduate Institute of Medical Sciences and Research (IN), Employees' State Insurance Model Hospital (IN)
Good health and well-being
Openalex Percentile: Top 94%
Ovarian cancer diagnosis and treatment
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Correlation Between Histopathology and Chemotherapy Response in Epithelial Ovarian Tumors — T Sravanthi, M Ramya, et al. · Cureus (2026) | TGRS Research Map | TGRS