A Comprehensive Review of Designing and Synthetic Aspects of Pyrazolopyrimidine Derivatives as Anticancer Agents

Pyrazolopyrimidines represent a versatile and promising class with strong in vivo efficacy, selectivity, and a favorable toxicity profile. Their ability to engage multiple targets and overcome resistance highlights their potential for integration in oncology. However, further systematic in vivo and clinical studies are essential to translate their potential into therapeutic success.