STAT wars: how STATopathies sabotage innate immunity

Recognition of innate immune dysregulation as an important driver of STATopathies broadens diagnostic and therapeutic horizons. Integrating innate immune profiling into clinical evaluation may refine prognostication and treatment selection, while mechanistic understanding of STAT control in myeloid lineages paves the way for precision immunomodulation and future curative interventions.

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Publication Details

Journal
Current Opinion in Allergy and Clinical Immunology
Published
2026-01-06
DOI
https://doi.org/10.1097/aci.0000000000001139
Citations
1
Primary Topic
Immunodeficiency and Autoimmune Disorders
Type
article
Field-Weighted Citation Impact
24.43
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article

STAT wars: how STATopathies sabotage innate immunity

Zuzana Paračková, Klára Šabatková, Markéta Bloomfield
1 citations
Current Opinion in Allergy and Clinical Immunology
Immunodeficiency and Autoimmune Disorders
24.43
article

STAT wars: how STATopathies sabotage innate immunity

Zuzana Paračková, Klára Šabatková, Markéta Bloomfield
article en
1 citations

Abstract

Recognition of innate immune dysregulation as an important driver of STATopathies broadens diagnostic and therapeutic horizons. Integrating innate immune profiling into clinical evaluation may refine prognostication and treatment selection, while mechanistic understanding of STAT control in myeloid lineages paves the way for precision immunomodulation and future curative interventions.

Current Opinion in Allergy and Clinical ImmunologyVol. 26(2)
University Hospital in Motol (CZ), Mother Hospital (IN), Thomayer University Hospital (CZ)
Openalex Percentile: Top 3%
Immunodeficiency and Autoimmune Disorders
24.43
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