The effectiveness of 100 mg aspirin in preventing superimposed preeclampsia in women with chronic hypertension: a real-world study
Our study suggests that initiating 100 mg/day of aspirin between 12 and 20 weeks of gestation does not significantly reduce superimposed PE in women with CHTN; however, it significantly reduces the risk of SGA. Subgroup analyses also indicated that even initiation before 16 weeks did not provide additional preventive effect against PE.
Authors
- Yanli Qiao
- Yawen Chen
- Hongliang Mei (ORCID: https://orcid.org/0000-0002-9625-0260)
- Qiaoling Gu
- Jingjing Kan
- Haixia Zhang
- Yechao Chen
Institutions
- Nanjing Drum Tower Hospital (CN)
- Gansu Provincial Maternal and Child Health Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2026-01-09
- DOI
- https://doi.org/10.1186/s12884-025-08535-7
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00