A Medically Managed Case of Acromegaly: A Case Report

Endocrine glands are specialized cells responsible for producing and secreting hormones that serve many functions in various body tissues. The pituitary gland is an endocrine gland located in the brain, composed of anterior and posterior parts, both of which are responsible for the secretion of many hormones. The anterior pituitary gland secretes six hormones. Hypersecretion and undersecretion result in abnormalities in the body. Autonomous growth hormone production due to a pituitary adenoma leads to various changes in tissues and organs. Excess growth hormone results in gigantism during childhood, while in adulthood, it is called acromegaly. In this report, we present a 39-year-old man with a large somatotroph macroadenoma, which was managed entirely with medical therapy, resulting in significant biochemical and anatomical improvement. This case highlights the potential role of combined somatostatin analogs and dopamine agonists in selected patients with acromegaly.

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Journal
Cureus
Published
2026-01-09
DOI
https://doi.org/10.7759/cureus.101136
Primary Topic
Pituitary Gland Disorders and Treatments
Type
article
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article

A Medically Managed Case of Acromegaly: A Case Report

Rania Atallah Al-Asa'd, Karam Bdour, Nesreen el issa, Khaldon Al-Sarihin et al.
Cureus
Pituitary Gland Disorders and Treatments
article

A Medically Managed Case of Acromegaly: A Case Report

Rania Atallah Al-Asa'd, Karam Bdour, Nesreen el issa, Khaldon Al-Sarihin, Mohammad Albadarneh, Odai Alwraikat, Mu'taz Alwadi
article en

Abstract

Endocrine glands are specialized cells responsible for producing and secreting hormones that serve many functions in various body tissues. The pituitary gland is an endocrine gland located in the brain, composed of anterior and posterior parts, both of which are responsible for the secretion of many hormones. The anterior pituitary gland secretes six hormones. Hypersecretion and undersecretion result in abnormalities in the body. Autonomous growth hormone production due to a pituitary adenoma leads to various changes in tissues and organs. Excess growth hormone results in gigantism during childhood, while in adulthood, it is called acromegaly. In this report, we present a 39-year-old man with a large somatotroph macroadenoma, which was managed entirely with medical therapy, resulting in significant biochemical and anatomical improvement. This case highlights the potential role of combined somatostatin analogs and dopamine agonists in selected patients with acromegaly.

CureusVol. 18(1)
King Hussein Medical Center (JO)
Good health and well-being
Openalex Percentile: Top 94%
Pituitary Gland Disorders and Treatments
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A Medically Managed Case of Acromegaly: A Case Report — Rania Atallah Al-Asa'd, Karam Bdour, et al. · Cureus (2026) | TGRS Research Map | TGRS