The telomeric puzzle in <i>TP53</i> -mutant myeloid neoplasms

In this issue of Blood, Guarnera et al 1 report that telomere content (TC) in specific myeloid neoplasm subgroups (particularly those with complex karyotype and biallelic TP53 mutations) is unexpectedly similar to that in nonmalignant controls, whereas overall myeloid neoplasms generally have lower TC.

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Publication Details

Journal
Blood
Published
2026-01-08
DOI
https://doi.org/10.1182/blood.2025031124
Primary Topic
Acute Myeloid Leukemia Research
Type
article
Field-Weighted Citation Impact
0.00
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article

The telomeric puzzle in TP53 -mutant myeloid neoplasms

Lucy C. Fox, Ing Soo Tiong
Blood
Acute Myeloid Leukemia Research
article

The telomeric puzzle in TP53 -mutant myeloid neoplasms

Lucy C. Fox, Ing Soo Tiong
article en

Abstract

In this issue of Blood, Guarnera et al 1 report that telomere content (TC) in specific myeloid neoplasm subgroups (particularly those with complex karyotype and biallelic TP53 mutations) is unexpectedly similar to that in nonmalignant controls, whereas overall myeloid neoplasms generally have lower TC.

BloodVol. 147(2)
The University of Melbourne (AU), Peter MacCallum Cancer Centre (AU)
Zero hunger
Openalex Percentile: Top 94%
Acute Myeloid Leukemia Research
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The telomeric puzzle in <i>TP53</i> -mutant myeloid neoplasms — Lucy C. Fox, Ing Soo Tiong · Blood (2026) | TGRS Research Map | TGRS