A Simplified Score for Extended Donor Criteria in Times of Organ Shortage
This study identifies key donor and recipient factors associated with 3-year survival after LT in Germany. Rescue allocation was frequently applied and unexpectedly associated with improved survival outcomes in this cohort. The hazard score, showing moderate discrimination (C-index = 0.62), should be regarded as an exploratory clinical decision support tool requiring external validation. These findings highlight the complexity of organ allocation under the current LAS system and underscore the need for ongoing evaluation of LAS policies in settings of organ shortage.
Authors
- Isabell Anna Just (ORCID: https://orcid.org/0000-0003-1141-9387)
- C. Knosalla
- Friedrich Welz (ORCID: https://orcid.org/0009-0004-9790-6884)
- Julia Stein (ORCID: https://orcid.org/0000-0002-9132-8073)
- Martin Witzenrath
- Felix Schoenrath
- Paul Juergen Schmidt-Hellinger
Institutions
- Humboldt-Universität zu Berlin (DE)
- Deutsches Herzzentrum der Charité (DE)
- German Centre for Cardiovascular Research (DE)
- German Center for Lung Research (DE)
- Universities of Giessen and Marburg Lung Center (DE)
- Deutsches Herzzentrum München (DE)
- Berlin Heart (Germany) (DE)
- Freie Universität Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Respiration
- Published
- 2026-01-08
- DOI
- https://doi.org/10.1159/000550215
- Primary Topic
- Transplantation: Methods and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00