Advances in the treatment of large granular lymphocytic leukemia

LGLL management is undergoing a paradigm shift with the emergence of multiple targeted therapeutic approaches. Future progress will depend on better prognostic stratification, better integration of disease and patient heterogeneity, and the development of personalized treatment strategies, potentially supported by molecular monitoring.

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Publication Details

Journal
Expert Review of Hematology
Published
2026-01-09
DOI
https://doi.org/10.1080/17474086.2026.2613733
Primary Topic
Chronic Lymphocytic Leukemia Research
Type
article
Field-Weighted Citation Impact
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article

Advances in the treatment of large granular lymphocytic leukemia

Mathilde Guégan, Thierry Lamy
Expert Review of Hematology
Chronic Lymphocytic Leukemia Research
article

Advances in the treatment of large granular lymphocytic leukemia

Mathilde Guégan, Thierry Lamy
article en

Abstract

LGLL management is undergoing a paradigm shift with the emergence of multiple targeted therapeutic approaches. Future progress will depend on better prognostic stratification, better integration of disease and patient heterogeneity, and the development of personalized treatment strategies, potentially supported by molecular monitoring.

Expert Review of HematologyVol. 19(3)
Inserm (FR), Université Rennes 2 (FR), Établissement Français du Sang (FR), Centre Hospitalier Universitaire de Rennes (FR)
Good health and well-being
Openalex Percentile: Top 94%
Chronic Lymphocytic Leukemia Research
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