Multi-omics profiling of chromatin accessibility and H3K27ac reveals super-enhancer–mediated regulatory networks governing endometrial receptivity in goats

Our data provided an integrated epigenomic atlas of endometrial receptivity establishment in goats and identify candidate regulatory elements and transcription factors that may orchestrate uterine preparation for implantation. These findings offer valuable insights and testable targets for improving fertility in ruminant livestock.

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Publication Details

Journal
Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
Published
2026-01-09
DOI
https://doi.org/10.1186/s40104-025-01318-2
Primary Topic
Reproductive System and Pregnancy
Type
article
Field-Weighted Citation Impact
0.00
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article

Multi-omics profiling of chromatin accessibility and H3K27ac reveals super-enhancer–mediated regulatory networks governing endometrial receptivity in goats

Songjian Yang, Yu Zhao, Zhipeng Sun, Junyin Zhao et al.
Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
Reproductive System and Pregnancy
article

Multi-omics profiling of chromatin accessibility and H3K27ac reveals super-enhancer–mediated regulatory networks governing endometrial receptivity in goats

Songjian Yang, Yu Zhao, Zhipeng Sun, Junyin Zhao, Mingming Wang, Xingqiang Fang, Yuhao Liao, Houmo Yu, Yuqin Cheng
article en

Abstract

Our data provided an integrated epigenomic atlas of endometrial receptivity establishment in goats and identify candidate regulatory elements and transcription factors that may orchestrate uterine preparation for implantation. These findings offer valuable insights and testable targets for improving fertility in ruminant livestock.

Journal of Animal Science and Biotechnology/Journal of animal science and biotechnologyVol. 17(1)
Southwest University (CN)
Openalex Percentile: Top 93%
Reproductive System and Pregnancy
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