<scp>MRONJ</scp> Risk Related to Dental Implants in Osteoporosis Treated With Denosumab: A Systematic Review

The current literature shows high heterogeneity, small sample sizes, and a lack of standardization, making it difficult to draw definitive conclusions. However, despite MRONJ being relatively rare, important factors were identified that could influence outcomes, such as transitioning from bisphosphonates to denosumab therapy, timing of implant placement, and the presence of peri-implantitis.

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Publication Details

Journal
Oral Diseases
Published
2026-01-08
DOI
https://doi.org/10.1111/odi.70181
Primary Topic
Bone health and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

MRONJ Risk Related to Dental Implants in Osteoporosis Treated With Denosumab: A Systematic Review

Matteo Biasotto, Katia Rupel, Roberto Di Lenarda, Rebheca Maria Pereira Santos
Oral Diseases
Bone health and treatments
article

MRONJ Risk Related to Dental Implants in Osteoporosis Treated With Denosumab: A Systematic Review

Matteo Biasotto, Katia Rupel, Roberto Di Lenarda, Rebheca Maria Pereira Santos
article en

Abstract

The current literature shows high heterogeneity, small sample sizes, and a lack of standardization, making it difficult to draw definitive conclusions. However, despite MRONJ being relatively rare, important factors were identified that could influence outcomes, such as transitioning from bisphosphonates to denosumab therapy, timing of implant placement, and the presence of peri-implantitis.

Oral Diseases
University of Trieste (IT), ASL Roma (IT), Azienda Sanitaria Universitaria Integrata di Trieste (IT)
Openalex Percentile: Top 94%
Bone health and treatments
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