Hepatobiliary adverse drug reactions during treatment with olaparib: an analysis of data from the EudraVigilance reporting system

Further pharmacovigilance studies are needed to evaluate the hepatic safety profile of olaparib. Investigating the pathophysiological mechanisms underlying olaparib-induced liver injury could offer clinicians valuable insights for its prevention and management.

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Publication Details

Journal
Frontiers in Drug Safety and Regulation
Published
2026-01-09
DOI
https://doi.org/10.3389/fdsfr.2025.1736759
Citations
1
Primary Topic
PARP inhibition in cancer therapy
Type
article
Field-Weighted Citation Impact
24.20
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article

Hepatobiliary adverse drug reactions during treatment with olaparib: an analysis of data from the EudraVigilance reporting system

Cecilia Cagnotta, Antonietta Anatriello, Maria Giuseppa Sullo, Elena-Mirabela Velişcu et al.
1 citations
Frontiers in Drug Safety and Regulation
PARP inhibition in cancer therapy
24.20
article

Hepatobiliary adverse drug reactions during treatment with olaparib: an analysis of data from the EudraVigilance reporting system

Cecilia Cagnotta, Antonietta Anatriello, Maria Giuseppa Sullo, Elena-Mirabela Velişcu, Cristina Scavone
article en
1 citations

Abstract

Further pharmacovigilance studies are needed to evaluate the hepatic safety profile of olaparib. Investigating the pathophysiological mechanisms underlying olaparib-induced liver injury could offer clinicians valuable insights for its prevention and management.

Frontiers in Drug Safety and RegulationVol. 5
Inserm (FR), Regione Campania (IT), Centre Hospitalier Universitaire de Bordeaux (FR), Bordeaux Population Health (FR), University of Campania "Luigi Vanvitelli" (IT), Link Campus University (IT)
Good health and well-being
Openalex Percentile: Top 3%
PARP inhibition in cancer therapy
24.20
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