Rectal neuroendocrine tumors: Update

Rectal neuroendocrine tumors (NETs) are increasingly detected and are the most common gastrointestinal NET sites. Often discovered incidentally during endoscopy, most are small, well differentiated, and have an excellent prognosis. Local resection is typically considered curative. Several guidelines, namely the European Neuroendocrine Tumor Society guidelines 2023, National Comprehensive Cancer network 2025, and the Polish Network of Neuroendocrine Tumors (2017) emphasize the use of endoscopic and endoscopic ultrasound staging to select the appropriate therapy, ranging from resection to advanced techniques for larger or metastatic diseases, highlighting the need for an accurate initial assessment.

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Publication Details

Journal
World Journal of Gastrointestinal Oncology
Published
2026-01-09
DOI
https://doi.org/10.4251/wjgo.v18.i1.114818
Primary Topic
Neuroendocrine Tumor Research Advances
Type
article
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article

Rectal neuroendocrine tumors: Update

Yasir Khayyat, Mohammed Khayyat
World Journal of Gastrointestinal Oncology
Neuroendocrine Tumor Research Advances
article

Rectal neuroendocrine tumors: Update

Yasir Khayyat, Mohammed Khayyat
article en

Abstract

Rectal neuroendocrine tumors (NETs) are increasingly detected and are the most common gastrointestinal NET sites. Often discovered incidentally during endoscopy, most are small, well differentiated, and have an excellent prognosis. Local resection is typically considered curative. Several guidelines, namely the European Neuroendocrine Tumor Society guidelines 2023, National Comprehensive Cancer network 2025, and the Polish Network of Neuroendocrine Tumors (2017) emphasize the use of endoscopic and endoscopic ultrasound staging to select the appropriate therapy, ranging from resection to advanced techniques for larger or metastatic diseases, highlighting the need for an accurate initial assessment.

World Journal of Gastrointestinal OncologyVol. 18(1)
King Abdulaziz University (SA), Umm al-Qura University (SA), King Abdulaziz Hospital (SA)
Good health and well-being
Openalex Percentile: Top 95%
Neuroendocrine Tumor Research Advances
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