17 02 Base Architecture Metastasis Esophageal Adenocarcinoma

The classical view of metastasis as stochastic seeding followed by clonal expansion is mechanistically incomplete. I propose a reframing and expansion of the model: metastatic colonization is the establishment of site-specific equilibria under drastically different biochemical constraints. This Model Tries to Map the corelatioan and evolution of the metastasis of this carcinoma , trying to show the dynamic that arisises and establishes itself in varios sites.