A narrow therapeutic window of platelet P2Y <sub>12</sub> reactivity in high-risk Chinese percutaneous coronary intervention patients

Our results suggest that high-risk Chinese PCI patients have a narrow therapeutic window. Within this window, high-risk patients are at lower risk for both ischemic and bleeding events. Platelet reactivity may have significant implications for personalized antiplatelet therapy in high-risk patients.

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Publication Details

Journal
PeerJ
Published
2026-01-09
DOI
https://doi.org/10.7717/peerj.20536
Primary Topic
Antiplatelet Therapy and Cardiovascular Diseases
Type
article
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0.00
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article

A narrow therapeutic window of platelet P2Y 12 reactivity in high-risk Chinese percutaneous coronary intervention patients

Z Y Wang, Jingle Li, Yaxin Liu, Huiling Song et al.
PeerJ
Antiplatelet Therapy and Cardiovascular Diseases
article

A narrow therapeutic window of platelet P2Y 12 reactivity in high-risk Chinese percutaneous coronary intervention patients

Z Y Wang, Jingle Li, Yaxin Liu, Huiling Song, Liying Gong, Shiming Tan, Guoping Yang, Yun Kuang, Yu Cao
article en

Abstract

Our results suggest that high-risk Chinese PCI patients have a narrow therapeutic window. Within this window, high-risk patients are at lower risk for both ischemic and bleeding events. Platelet reactivity may have significant implications for personalized antiplatelet therapy in high-risk patients.

PeerJVol. 14
Central South University (CN), Third Xiangya Hospital (CN)
Reduced inequalities
Openalex Percentile: Top 94%
Antiplatelet Therapy and Cardiovascular Diseases
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