Multi-isocentric volumetric arc-based total body irradiation: radiation dose impact on oncological outcomes in patients receiving allogeneic hematopoietic cell transplantation
In patients receiving modern TBI before allo-HCT with high-quality dose distribution, 12 Gy appears to be more effective than 8 Gy. However, this concerns a single-center cohort with TBI dose allocation according to estimated patient fragility before transplant. Therefore, randomized trials are required to determine the optimal RT dose.
Authors
- Joanna Kamińska
- A Romanowska
- Renata Zaucha
- Anita Prawdzik–Dampc
- Alicja Sadowska-Klasa
Institutions
- University of Gdańsk (PL)
- University Clinical Centre (PL)
- Gdańsk Medical University (PL)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-01-09
- DOI
- https://doi.org/10.3389/fonc.2025.1695178
- Primary Topic
- Hematopoietic Stem Cell Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00