Effectiveness and mechanisms of lymphocytes at different time points in predicting consolidation immunotherapy following adaptive chemoradiotherapy in locally advanced non-small cell lung cancer
In patients with locally advanced NSCLC receiving chemoradiotherapy followed by consolidation immunotherapy, higher ALCs and elevated CD8+ T-cell counts at 1 month post-chemoradiotherapy are associated with improved overall survival.
Authors
- S. Kevin Zhou (ORCID: https://orcid.org/0000-0002-6881-4444)
- J. Zhao (ORCID: https://orcid.org/0000-0001-6408-2314)
- De Zhou (ORCID: https://orcid.org/0000-0002-3698-2750)
- Meng Chen (ORCID: https://orcid.org/0000-0002-7190-2162)
- Haihua Yang
- Liqiao Hou
- Jiayi Duan
- Zhen wei Sun
- Jian Zhu
- Pingjun Gu
Institutions
- Wenzhou Medical University (CN)
- Taizhou Central Hospital (CN)
- Zhejiang Taizhou Hospital (CN)
- Taizhou University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-01-09
- DOI
- https://doi.org/10.3389/fonc.2025.1683430
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Technology Program of Zhejiang Province