The impact of individualized CT contrast media protocols on total iodine load and contrast enhancement: a systematic review and meta-analysis
Individualized contrast administration protocols significantly reduce total iodine load while maintaining non-inferior contrast enhancement and substantially reducing inter-patient variability. These findings support wider adoption of patient-tailored contrast dosing to optimize resource use and harmonize image quality.
Authors
- Thomas P. W. van den Boogert
- Fabian Rengier (ORCID: https://orcid.org/0000-0001-9424-4652)
- Oisín Butler (ORCID: https://orcid.org/0000-0001-6462-1664)
- Casper Mihl (ORCID: https://orcid.org/0000-0003-1348-6970)
- R.Nils Planken
- Johannes Thuering
- Alexander Ullmann
- Caren Pieritz
Institutions
- Maastricht University Medical Centre (NL)
- Maastricht University (NL)
- Amsterdam University Medical Centers (NL)
- Bayer (Germany) (DE)
Publication Details
- Journal
- Clinical Radiology
- Published
- 2026-01-08
- DOI
- https://doi.org/10.1016/j.crad.2026.107247
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00