Early antioxidant capacity, intestinal barrier integrity and gut microbiota drive DHAV-3 resistance in ducks
DHAV-3 resistant ducks exhibit early advantages in antioxidant defense, intestinal barrier development and colonization by beneficial microbiota, which collectively contribute to enhanced disease resistance. These findings highlight the synergistic roles of host physiology and gut microbiota in shaping resistance. In the future, integrating genomic selection with microbiota modulation and antioxidant interventions may accelerate the breeding of highly resistant duck lines and provide scientific evidence and practical strategies for controlling duck viral hepatitis.
Authors
- Zhenwei Zhou (ORCID: https://orcid.org/0000-0002-1940-2697)
- Tong Xu (ORCID: https://orcid.org/0000-0002-5032-1318)
- Wen Zhiguo
- Yan Wu (ORCID: https://orcid.org/0000-0001-6177-9132)
- Hou Shuisheng
- Yunsheng Zhang (ORCID: https://orcid.org/0000-0002-4748-1548)
- Qimeng Wang (ORCID: https://orcid.org/0000-0001-6453-7358)
- Cao Junting
- Bo Zhang
- Yanhong Guo
- Yiwen Yang
Institutions
- Chinese Academy of Agricultural Sciences (CN)
- Beijing Academy of Agricultural and Forestry Sciences (CN)
- Feed Research Institute (CN)
- Institute of Animal Sciences (CN)
- Ministry of Agriculture and Rural Affairs (CN)
Publication Details
- Journal
- Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
- Published
- 2026-01-09
- DOI
- https://doi.org/10.1186/s40104-025-01329-z
- Primary Topic
- Animal Virus Infections Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00