Genetic evidence for causal associations of thrombohemostasis and anticoagulant drug targets with miscarriage

These findings do not support a causal role for thrombohemostatic factors or routine anticoagulant therapy in miscarriage prevention, underscoring the complexity of miscarriage etiology. Precision medicine approaches based on validated biomarkers might be necessary to identify women most likely to benefit from targeted interventions.

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Publication Details

Journal
International Journal of Gynecology & Obstetrics
Published
2026-01-09
DOI
https://doi.org/10.1002/ijgo.70792
Primary Topic
Blood Coagulation and Thrombosis Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Genetic evidence for causal associations of thrombohemostasis and anticoagulant drug targets with miscarriage

Jing Zhang, Sihui Yu, Hao Wu, Jiawen Zhang
International Journal of Gynecology & Obstetrics
Blood Coagulation and Thrombosis Mechanisms
article

Genetic evidence for causal associations of thrombohemostasis and anticoagulant drug targets with miscarriage

Jing Zhang, Sihui Yu, Hao Wu, Jiawen Zhang
article en

Abstract

These findings do not support a causal role for thrombohemostatic factors or routine anticoagulant therapy in miscarriage prevention, underscoring the complexity of miscarriage etiology. Precision medicine approaches based on validated biomarkers might be necessary to identify women most likely to benefit from targeted interventions.

International Journal of Gynecology & Obstetrics
Shanghai Jiao Tong University (CN), Fudan University (CN), Shanghai Mental Health Center (CN), Zhongshan Hospital (CN)
Good health and well-being
Openalex Percentile: Top 94%
Blood Coagulation and Thrombosis Mechanisms
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