Divergent oxidative annulation of primary aliphatic amines to access semi-saturated fused pyrimidines or quinazolines
A novel multicomponent reaction enables the divergent synthesis of semi-saturated fused pyrimidines and quinazolines from cycloalkylamines, aldehydes and NH 4 I via oxidative annulation involving C(sp 3 )–H functionalization of primary aliphatic amines.
Authors
- Jinjin Chen
- Fanqian Li
- J. Li
- Guo-Jun Deng
- Zhen Wang
- Xue Peng
- Yao-Fu Zeng
- Kang Liu
- Xinyi Tang
- Xinping Liu
Institutions
- Xiangtan University (CN)
- University of South China (CN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1039/d5qo01676b
- Primary Topic
- Quinazolinone synthesis and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00