A pilot study to assess the effect of integrating an automated speech‐based cognitive assessment into a brain health platform on PCP visits

Abstract Background Alzheimer's disease is underdiagnosed, and symptoms are regularly detected late in the disease progression, highlighting the need for efficient screening options. One promising digital detection tool is the speech biomarker for cognition (ki:e SB‐C), which effectively detects memory impairment linked to Alzheimer's (Tröger et al., 2022). The BrainGuide ® platform by UsAgainstAlzheimer's reaches tens of thousands of people annually who are interested in their brain health. Integrating ki:e SB‐C into this widely used brain health platform could promote screening, encourage at‐risk users to seek evaluation from a primary care physician (PCP) and allow evaluation of efficacy. Method The ki:e SB‐C was integrated into the BrainGuide platform, where users could access information and complete the ki:e SB‐C remotely. After completing the assessment, users received a report with their score and based on normative data, an estimation of their cognitive risk (low, medium, or high). Users were also invited to rate the usability of the assessment and indicate whether they planned to consult a doctor. User behavior, usability ratings, and ki:e SB‐C scores from a 10‐week trial period were then analyzed. Result Out of 416 users (28%) who began the SB‐C assessment on BrainGuide, 154 completed it. The mean SB‐C score was 0.37 ± 0.32 (range 0‐1). Risk scores were: 42% high, 32% medium, and 26% low. Fifteen users rated usability, with an average score of 8.8/10. Of the 50 users who answered whether they would consult a doctor about memory concerns, 31 agreed. The study is ongoing. Conclusion Individuals concerned about their cognition who visit a brain health web platform are generally open to taking a speech‐based test. Nearly 75% of those who completed the test performed in a range for their age and education that indicates moderate or high risk of impairment. Early findings indicate that the assessment might also influence the willingness to make an appointment with a PCP.

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Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_107056
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
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article

A pilot study to assess the effect of integrating an automated speech‐based cognitive assessment into a brain health platform on PCP visits

Russ Paulsen, Simona Schäfer, Vera Maljkovic, Vivian Vasallo et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

A pilot study to assess the effect of integrating an automated speech‐based cognitive assessment into a brain health platform on PCP visits

Russ Paulsen, Simona Schäfer, Vera Maljkovic, Vivian Vasallo, Nicklas Linz, Kay Bhothinard
article en

Abstract

Abstract Background Alzheimer's disease is underdiagnosed, and symptoms are regularly detected late in the disease progression, highlighting the need for efficient screening options. One promising digital detection tool is the speech biomarker for cognition (ki:e SB‐C), which effectively detects memory impairment linked to Alzheimer's (Tröger et al., 2022). The BrainGuide ® platform by UsAgainstAlzheimer's reaches tens of thousands of people annually who are interested in their brain health. Integrating ki:e SB‐C into this widely used brain health platform could promote screening, encourage at‐risk users to seek evaluation from a primary care physician (PCP) and allow evaluation of efficacy. Method The ki:e SB‐C was integrated into the BrainGuide platform, where users could access information and complete the ki:e SB‐C remotely. After completing the assessment, users received a report with their score and based on normative data, an estimation of their cognitive risk (low, medium, or high). Users were also invited to rate the usability of the assessment and indicate whether they planned to consult a doctor. User behavior, usability ratings, and ki:e SB‐C scores from a 10‐week trial period were then analyzed. Result Out of 416 users (28%) who began the SB‐C assessment on BrainGuide, 154 completed it. The mean SB‐C score was 0.37 ± 0.32 (range 0‐1). Risk scores were: 42% high, 32% medium, and 26% low. Fifteen users rated usability, with an average score of 8.8/10. Of the 50 users who answered whether they would consult a doctor about memory concerns, 31 agreed. The study is ongoing. Conclusion Individuals concerned about their cognition who visit a brain health web platform are generally open to taking a speech‐based test. Nearly 75% of those who completed the test performed in a range for their age and education that indicates moderate or high risk of impairment. Early findings indicate that the assessment might also influence the willingness to make an appointment with a PCP.

Alzheimer s & DementiaVol. 21(S2)
UsAgainstAlzheimer (US), Eisai (United States) (US), Klinikum Saarbrücken (DE)
Quality Education
Openalex Percentile: Top 29%
Dementia and Cognitive Impairment Research
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