The value of quantitative fluorescence polymerase chain reaction for the products of conception in the era of copy number variation sequencing

QF-PCR can effectively complement the limitations of CNV-Seq. Employing QF-PCR to rule out maternal cell contamination prior to performing CNV-Seq on all samples is the best detection strategy.

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Publication Details

Journal
Frontiers in Genetics
Published
2026-01-08
DOI
https://doi.org/10.3389/fgene.2025.1750362
Primary Topic
Prenatal Screening and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00
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article

The value of quantitative fluorescence polymerase chain reaction for the products of conception in the era of copy number variation sequencing

Rongxiang Li, Q. Zhang, Hewei Zhang, Shaozhe Yang et al.
Frontiers in Genetics
Prenatal Screening and Diagnostics
article

The value of quantitative fluorescence polymerase chain reaction for the products of conception in the era of copy number variation sequencing

Rongxiang Li, Q. Zhang, Hewei Zhang, Shaozhe Yang, Xiuhong Fu, Yongyong Wu, Yongli Wang
article en

Abstract

QF-PCR can effectively complement the limitations of CNV-Seq. Employing QF-PCR to rule out maternal cell contamination prior to performing CNV-Seq on all samples is the best detection strategy.

Frontiers in GeneticsVol. 16
Luohe Medical College (CN)
Openalex Percentile: Top 94%
Prenatal Screening and Diagnostics
DOIOpen Access PDFOpenAlex
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The value of quantitative fluorescence polymerase chain reaction for the products of conception in the era of copy number variation sequencing — Rongxiang Li, Q. Zhang, et al. · Frontiers in Genetics (2026) | TGRS Research Map | TGRS