<scp>GLP1</scp> ‐ <scp>1RAs</scp> improve walking distance and reduce amputation in people with type 2 diabetes and peripheral artery disease: A systematic review and meta‐analysis of randomised controlled trials and cohort studies

This meta-analysis suggests that GLP-1RAs are associated with a significant improvement in functional walking distance and a reduction in the risk of LEA in people with type 2 and PAD. Further dedicated RCTs are needed to confirm these limb-specific benefits of GLP-1RAs.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2026-01-08
DOI
https://doi.org/10.1111/dom.70454
Primary Topic
Peripheral Artery Disease Management
Type
article
Field-Weighted Citation Impact
0.00
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article

GLP1 ‐ 1RAs improve walking distance and reduce amputation in people with type 2 diabetes and peripheral artery disease: A systematic review and meta‐analysis of randomised controlled trials and cohort studies

Maria Ida Maiorino, Miriam Longo, Paola Caruso, K. Esposito et al.
Diabetes Obesity and Metabolism
Peripheral Artery Disease Management
article

GLP1 ‐ 1RAs improve walking distance and reduce amputation in people with type 2 diabetes and peripheral artery disease: A systematic review and meta‐analysis of randomised controlled trials and cohort studies

Maria Ida Maiorino, Miriam Longo, Paola Caruso, K. Esposito, Nicole Di Martino, Dario Giugliano
article en

Abstract

This meta-analysis suggests that GLP-1RAs are associated with a significant improvement in functional walking distance and a reduction in the risk of LEA in people with type 2 and PAD. Further dedicated RCTs are needed to confirm these limb-specific benefits of GLP-1RAs.

Diabetes Obesity and MetabolismVol. 28(4)
University of Campania "Luigi Vanvitelli" (IT), University of Campania "Luigi Vanvitelli" (IT), Link Campus University (IT)
Good health and well-being
Openalex Percentile: Top 94%
Peripheral Artery Disease Management
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