Correlation between sub-phenotypes of coagulopathy and prognosis in sepsis patients in ICU using longitudinal group trajectory modeling: a retrospective analysis

Our study suggests that coagulopathy in sepsis patients can be classified into three distinct sub-phenotypes, each associated with different risks of 28-day mortality. Future prospective studies incorporating external validation and multiple specific parameters are needed to explore the mechanisms underlying these sub-phenotypes and validate their application in clinical practice.

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Publication Details

Journal
European journal of medical research
Published
2026-01-08
DOI
https://doi.org/10.1186/s40001-025-03779-7
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Correlation between sub-phenotypes of coagulopathy and prognosis in sepsis patients in ICU using longitudinal group trajectory modeling: a retrospective analysis

Xin Tie, Yao Qin, Jing Su, Wanhong Yin et al.
European journal of medical research
Sepsis Diagnosis and Treatment
article

Correlation between sub-phenotypes of coagulopathy and prognosis in sepsis patients in ICU using longitudinal group trajectory modeling: a retrospective analysis

Xin Tie, Yao Qin, Jing Su, Wanhong Yin, Yi Li, Xueying Zeng, Tongjuan Zou, Ran Zhou
article en

Abstract

Our study suggests that coagulopathy in sepsis patients can be classified into three distinct sub-phenotypes, each associated with different risks of 28-day mortality. Future prospective studies incorporating external validation and multiple specific parameters are needed to explore the mechanisms underlying these sub-phenotypes and validate their application in clinical practice.

European journal of medical researchVol. 31(1)
Sichuan University (CN), West China Hospital of Sichuan University (CN)
Good health and well-being
Openalex Percentile: Top 95%
Sepsis Diagnosis and Treatment
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