Spinal Pathologies Associated With Loeys-Dietz Syndrome: A Systematic Review

The most common spinal pathologies in LDS were scoliosis, cervical instability/deformity, dural ectasia, and spondylolisthesis. Most scoliosis cases did not require surgery. Cervical pathology and spondylolisthesis required surgery at higher rates in these patients, particularly when progressive and early-onset. There is a need for prospective, larger-cohort studies for these patients.

Authors

Publication Details

Journal
Global Spine Journal
Published
2026-01-09
DOI
https://doi.org/10.1177/21925682261416407
Primary Topic
Connective tissue disorders research
Type
article
Field-Weighted Citation Impact
0.00
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article

Spinal Pathologies Associated With Loeys-Dietz Syndrome: A Systematic Review

Alexander T. Yahanda, Alan C. Braverman, Camilo A. Molina
Global Spine Journal
Connective tissue disorders research
article

Spinal Pathologies Associated With Loeys-Dietz Syndrome: A Systematic Review

Alexander T. Yahanda, Alan C. Braverman, Camilo A. Molina
article en

Abstract

The most common spinal pathologies in LDS were scoliosis, cervical instability/deformity, dural ectasia, and spondylolisthesis. Most scoliosis cases did not require surgery. Cervical pathology and spondylolisthesis required surgery at higher rates in these patients, particularly when progressive and early-onset. There is a need for prospective, larger-cohort studies for these patients.

Global Spine Journal
Openalex Percentile: Top 94%
Connective tissue disorders research
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Spinal Pathologies Associated With Loeys-Dietz Syndrome: A Systematic Review — Alexander T. Yahanda, Alan C. Braverman, et al. · Global Spine Journal (2026) | TGRS Research Map | TGRS