A Comprehensive Assessment of Health-Related Quality of Life in Hereditary Angioedema as a Patient-Centered Approach
While attack frequency and disease control remain the primary determinants of HRQoL in HAE-C1INH, our findings indicate that attack localization is associated with distinct domain-specific quality-of-life impairments. Beyond assessing attack frequency, the use of disease-specific QoL tools allows for the identification of domain-specific impairments. Personalized treatment strategies targeting both symptom control and quality-of-life domains are essential for alleviating the long-term burden on patients and their families.
Authors
- Esra KARABİBER
- Esra Yücel (ORCID: https://orcid.org/0000-0003-3712-2522)
- Safa Baris
- Ümmügülsüm Dikici (ORCID: https://orcid.org/0000-0002-7435-1108)
- Melek Yorgun Altunbaş (ORCID: https://orcid.org/0000-0002-4832-2928)
- Ece Tüsüz Önata (ORCID: https://orcid.org/0000-0002-0180-9093)
- Ebru Arik Yilmaz
- Necmiye Öztürk
- Razin Amirov
- Ayca Kiykim
- Metin Aydogan
- Ismail Ozanli
- Ozge Atik
- Sevgi Bilgic-Eltan
- Isil Eser Simsek
- Selcen Bozkurt
- Salim Can
- Fatma Merve Tepetam
- Emine Nihal Mete Gokmenk
- Ahmet Ozen
- Gulhan Bogatekin
- Oner Ozdemir
- Ezgi Yalcin Gungoren
Institutions
- University of Health Science (KH)
- Ege University (TR)
- Istanbul University-Cerrahpaşa (TR)
- Sakarya Eğitim ve Araştırma Hastanesi (TR)
- Sağlık Bilimleri Üniversitesi (TR)
- Jeffrey Modell Foundation (AU)
- Pamukkale University (TR)
- Kocaeli Üniversitesi (TR)
- Istanbul University (TR)
- Marmara University (TR)
- University of Health Sciences Antigua (AG)
Publication Details
- Journal
- International Archives of Allergy and Immunology
- Published
- 2026-01-08
- DOI
- https://doi.org/10.1159/000550399
- Primary Topic
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Type
- article
- Field-Weighted Citation Impact
- 0.00