Characterization of two novel bacteriophages infecting clinical isolates of <i>Serratia</i> spp. and therapeutic efficacy in a <i>Galleria mellonella</i> model of infection

Sm10b_1 and Sm12 represent novel lytic phages with broad host ranges against clinical isolates of the genus Serratia. Sm10b_1 was found to be highly effective at treating experimental infections caused by S. marcescens and S. odorifera.

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Publication Details

Journal
Journal of Applied Microbiology
Published
2026-01-09
DOI
https://doi.org/10.1093/jambio/lxag011
Primary Topic
Bacteriophages and microbial interactions
Type
article
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article

Characterization of two novel bacteriophages infecting clinical isolates of Serratia spp. and therapeutic efficacy in a Galleria mellonella model of infection

David Negus, Caitlin Wildsmith, Lesley Hoyles, Yashwani Malik et al.
Journal of Applied Microbiology
Bacteriophages and microbial interactions
article

Characterization of two novel bacteriophages infecting clinical isolates of Serratia spp. and therapeutic efficacy in a Galleria mellonella model of infection

David Negus, Caitlin Wildsmith, Lesley Hoyles, Yashwani Malik, Mohamed Eladawy, Mia Horton
article en

Abstract

Sm10b_1 and Sm12 represent novel lytic phages with broad host ranges against clinical isolates of the genus Serratia. Sm10b_1 was found to be highly effective at treating experimental infections caused by S. marcescens and S. odorifera.

Journal of Applied MicrobiologyVol. 137(2)
Mansoura University (EG), Nottingham Trent University (GB)
Clean water and sanitation
Openalex Percentile: Top 95%
Bacteriophages and microbial interactions
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