Leaping forward: how China’s biotech evolution is capturing the <i>in vivo</i> CAR-T frontier

“Ultimately, the goal remains consistent: addressing large unmet medical needs through whatever combination of global and local capabilities proves most effective.” Yu (Clay) Cao, Vice President, Global Head of Drug Discovery, GenEditBio and Guest Editor of Cell & Gene Therapy Insights’ February edition speaks with Zhenghong Gao, Co-founder and COO of Uni-Pioneers Bio-Med, Inc., who examines the rise of in vivo CAR-T as a transformative modality within China’s rapidly evolving biotech ecosystem. The discussion highlights structural differences and complementarities between Chinese and Western innovation models, key technological and manufacturing challenges in delivery platforms, and the role of regulatory agility and evolving funding structures. Together, the conversation offers a forward-looking perspective on how global convergence may shape the next phase of gene and cell therapy innovation.

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Publication Details

Journal
Cell and Gene Therapy Insights
Published
2026-01-05
DOI
https://doi.org/10.18609/cgti.2026.002
Primary Topic
Biomedical Ethics and Regulation
Type
article
Field-Weighted Citation Impact
0.00
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article

Leaping forward: how China’s biotech evolution is capturing the in vivo CAR-T frontier

Zhenghong Gao
Cell and Gene Therapy Insights
Biomedical Ethics and Regulation
article

Leaping forward: how China’s biotech evolution is capturing the in vivo CAR-T frontier

Zhenghong Gao
article en

Abstract

“Ultimately, the goal remains consistent: addressing large unmet medical needs through whatever combination of global and local capabilities proves most effective.” Yu (Clay) Cao, Vice President, Global Head of Drug Discovery, GenEditBio and Guest Editor of Cell & Gene Therapy Insights’ February edition speaks with Zhenghong Gao, Co-founder and COO of Uni-Pioneers Bio-Med, Inc., who examines the rise of in vivo CAR-T as a transformative modality within China’s rapidly evolving biotech ecosystem. The discussion highlights structural differences and complementarities between Chinese and Western innovation models, key technological and manufacturing challenges in delivery platforms, and the role of regulatory agility and evolving funding structures. Together, the conversation offers a forward-looking perspective on how global convergence may shape the next phase of gene and cell therapy innovation.

Cell and Gene Therapy InsightsVol. 12(1)
United Therapeutics (United States) (US)
Industry, innovation and infrastructure
Openalex Percentile: Top 94%
Biomedical Ethics and Regulation
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