Comparative landscape of small RNAs in tissue and liquid biopsies for liver transplant outcomes
These results are the first to establish tRFs as IRI-responsive biomolecules abundant in both donor liver tissue and non-invasive perfusate. In particular, various small RNAs emerged as promising candidate biomarkers for early detection of EAD. These results lay the foundation to further investigate the prognostic utility of tRFs/miRNAs in liver transplantation.
Authors
- Christine Watkins (ORCID: https://orcid.org/0000-0001-5341-6649)
- Grace M. Rucker
- Jason S. VanAtta
- Canan Kuscu (ORCID: https://orcid.org/0000-0002-8043-7960)
- Murat Doğan (ORCID: https://orcid.org/0000-0003-0002-8428)
- James D. Eason (ORCID: https://orcid.org/0000-0001-9011-5765)
- Corey Eymard (ORCID: https://orcid.org/0000-0001-8668-8333)
- Monima Anam
- Katherine Marlow
- Matthew Khalil
- Zhangli Su
- Cem Kuscu
Institutions
- University of Tennessee Health Science Center (US)
- University of Alabama at Birmingham (US)
- Methodist University Hospital (US)
Publication Details
- Journal
- Computational and Structural Biotechnology Journal
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1016/j.csbj.2026.01.005
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00