Two new iridoid glycosides from the roots of <i>Dipsacus asper</i>
Two new iridoid glycosides, dasperosides <b>A</b>-<b>B</b> (<b>1</b>-<b>2</b>), together with two known analogues (<b>3</b>-<b>4</b>), were isolated from the air-dried roots of <i>Dipsacus asper</i>. Their structures were established from the spectroscopic data obtained and chemical evidence. Compounds <b>1</b>-<b>4</b> were tested for their cytotoxicity against six human tumor cell lines, hepatoprotective and anti-inflammatory activities.
Authors
- Xiaoze Li
- Guo-Ru Shi
- Ming-Hui Sun
- Yanfei Liu
- Wanqi Zhang (ORCID: https://orcid.org/0000-0002-1552-2595)
- Gu Zhao
- De-Quan Yu
- Jie Zhou
- Jing-Han Zhang
- Xin-Li Ma
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Publication Details
- Journal
- Journal of Asian Natural Products Research
- Published
- 2026-01-09
- DOI
- https://doi.org/10.1080/10286020.2025.2608810
- Primary Topic
- Phytochemistry and Biological Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.00