Timing of endometrial biopsy for chronic endometritis diagnosis: CD138 <sup>+</sup> and CD56 <sup>+</sup> cell variability throughout the menstrual cycle

In patients with RPL or RIF, endometrial biopsy shows similar CD138+ and CD56+ positivity rates in both proliferative and secretive phases. These findings suggest that biopsy timing may not substantially affect detection rates.

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Publication Details

Journal
The European Journal of Contraception & Reproductive Health Care
Published
2026-01-09
DOI
https://doi.org/10.1080/13625187.2025.2600576
Primary Topic
Reproductive System and Pregnancy
Type
article
Field-Weighted Citation Impact
0.00
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article

Timing of endometrial biopsy for chronic endometritis diagnosis: CD138 + and CD56 + cell variability throughout the menstrual cycle

Maria Rosaria Campitiello, Antonio La Marca, Simone Giulini, Riccardo Cuoghi Costantini et al.
The European Journal of Contraception & Reproductive Health Care
Reproductive System and Pregnancy
article

Timing of endometrial biopsy for chronic endometritis diagnosis: CD138 + and CD56 + cell variability throughout the menstrual cycle

Maria Rosaria Campitiello, Antonio La Marca, Simone Giulini, Riccardo Cuoghi Costantini, Laura Botticelli, Sara Lazzarin, Maria Longo, Serena Lecis, Chiara Selmi, Isabella Neri, Francesca Monari, Giulia Tarozzi
article en

Abstract

In patients with RPL or RIF, endometrial biopsy shows similar CD138+ and CD56+ positivity rates in both proliferative and secretive phases. These findings suggest that biopsy timing may not substantially affect detection rates.

The European Journal of Contraception & Reproductive Health CareVol. 31(2)
ASL Roma (IT), Azienda Ospedaliero-Universitaria di Modena (IT)
Good health and well-being
Openalex Percentile: Top 93%
Reproductive System and Pregnancy
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